Resumen. DELGADO FERNANDEZ, María del Rosario; ROMERO RIVERO, Oscar Luis y DIAZ BORROTO, Abel. Central insipid diabetes: presentation of a case. Articulo en XML; Referencias del artículo; Como citar este artículo; SciELO Analytics; Enviar Neurohypophisis and Insipid Diabetes: A description of a case. Palabras clave: Neurohipófisis [Histología]; Diabetes Insípida [ Diagnóstico];. Existen dos tipos: diabetes insípida (DI) central, debida a la síntesis o liberación defectuosas de arginina vasopresina (AVP) desde el Artículos de referencia.
|Published (Last):||2 August 2015|
|PDF File Size:||15.6 Mb|
|ePub File Size:||9.99 Mb|
|Price:||Free* [*Free Regsitration Required]|
Todos ellos fueron intervenidos mediante un abordaje transesfenoidal. Pathology of invasive pituitary tumors with special reference to functional classification. See the new contents in http: The histological characteristics of the Neuro hypophysis are described as well as its morphological functions related to the hypothalamus.
We compare de resection grade versus invasion grade with exact Fisher test.
Can J Neurol Sci ; Variations on the standard transsphenoidal approach to the sellar region, with emphasis on the extended approaches and parasellar approaches: This may explain why indomethacin enhances the effect of the thiazides in patients with nephrogenic diabetes insipidus. In the former, the patient generally, because of psychological disorders, ingests large quantities of water and other fluids, which causes a compensatory polyuria and articuulos clinical picture similar to diabetes insipidus is seen, but without completely affecting the power of renal concentration.
Plasma levels of AVP.
NEUROHIPOFISIS Y DIABETES INSIPIDA: PRESENTACION DE UN CASO
Different ways to open and close the tap. The foregoing precludes progressive weight loss.
This disorder is caused by the failure of the posterior pituitary to secrete adequate amounts of arginine vasopressin AVPalso called antidiuretic hormone aryiculos or central diabetes insipidusor by the inability diabdtes the kidney to respond to circulating AVP nephrogenic diabetes insipidus.
Therefore, the episodes of hypernatremic dehydration begin. We describe the clinical course of a young lady who after her sixth childbirth developed severe postpartum hemorrhage followed by development of panhypopituitarism which was confirmed by hormonal investigation and demonstration of empty sella on imaging.
It is a nine amino acid peptide with an annular structure and a disulfuric connection.
Nephrogenic diabetes insipidus | Boletín Médico del Hospital Infantil de México (English Edition)
Younger children do not tolerate amiloride well due to the persistent feeling of nausea, for which it is probable they would require the combination with indomethacin in the first years of life. This results in water reabsorption in the collecting duct of the nephron following an osmotic gradient. En nuestra serie hemos conseguido resecciones completas en el grado 4. Tumours of the adenohypophysis.
The patient got better from her ID picture but she died because of her leukemia. Weight and urinary volume should be controlled each hour; if polyuria is great, weight control should be done every 30 min.
Thus, under the influence of the osmotic gradient of sodium, water is reabsorbed intracellularly, enters the cell through the aquaporin-2 water channel and exits the cell towards the interstitium through aquaporin-3 and aquaporin-4, which is located in the basolateral cell membrane Fig. The V 2 receptor, which is found in the vascular endothelium and in the principal cells of the connecting and collecting tubules of the nephron, induces the release of factor 8 and von Willebrand factor and mediates the hydro-osmotic effect of the AVP.
Incidence and management of complications of transsphenoidal operation for pituitary adenomas. AVP receptors differ both in their location as well as their functions Table 1.
Diverse medications affect the renal capacity for concentrating urine and cause variable degrees of polyuria. Previous article Next article. These patients characteristically present with a less severe clinical form of diabetes insipidus. Clin Neurosurg ; Based on more in-depth mechanistic understanding, new therapeutic strategies are current being explored. Congenital nephrogenic diabetes insipidus.
During a crisis episode in patients with anemia of falciform cells an increase in the viscosity of the blood may occur in the vasa recta of the renal medulla, altering the multiplier or interchange mechanisms of the counter current, decreasing the hypertonicity of the renal medulla and ibsipida polyuria with resistance to the antidiuretic hormone.
Among the different groups of patients with nephrogenic diabetes insipidus due to a secondary interstitial tubular disease, one of the most important is that caused by kaliopenic nephropathy which presents in children with severe malnutrition.
There was a problem providing the content you requested
The most important biological action of AVP is preservation of body water by reducing urinary output. In early presentations, the infant presents with persistent crying and irritability, stopping with ingestion of water or diluted milk. Twenty three operations were performed on twenty-two patients. Currently there is sufficient evidence to continue treatment with hydrochlorothiazide and amiloride 0. In contrast, the persistence of a lack of response corresponds to cases of nephrogenic diabetes insipidus Fig.
In females who present mutation of the AVPR2the phenotypic expression of the defect could be absent, partially present or complete. The shortage or deficit of antidiuretic hormones provokes the elimination of a great volumen of hypotonic diluted and tasteless urine; this disorder is known as insipid diabetes.
Studies for the treatment of congenital nephrogenic diabetes insipidus have been recently done through drug stimulation, promoting the transport of the AVPR2 onsipida in the cytoplasm of the tubulorenal cell to the plasma membrane where it could develop its function.
Predicitve value of the Knosp classification in the staging of invasive pituitary macroadenomas. There is no specific treatment when we are dealing with a primary disorder.
Increase in the permeability to water in the collecting tubule of the nephron implies action of the aquaporin-2 water channel in the apical membranes of the principal cells of this segment of the renal tubule.
Due to risk of developing extended urinary bladders due inslpida polyuria, the bladder should be emptied regularly to ensure the maximal bladder capacity is maintained within the normal range. Reduction of the expression diabdtes aquaporin-2 and of the function of the sodium transporters in the renal tubule: A decade of pituitary microsurgery.
A direct correlation between the plasma levels of AVP determined by radioimmunoassay and plasma osmolality after a concentration test in normal subjects has been demonstrated. Proliferation activity in pituitary adenomas: En la insippida, como podemos ver en la tabla 2, ninguno de los pacientes con resecciones totales o subtotales ha necesitado RDTEF.
In this manner, clinical scenarios of nephrogenic diabetes insipidus have been described in patients with juvenile nephronophtisis before the development of chronic renal failurein patients with polycystic kidney disease, distal renal tubular acidosis, Fanconi syndrome, idiopathic hypercalciuria and renal amyloidosis.