Dysbaric osteonecrosis (DON) is the destruction of bone tissue in the long bones, hips and shoulders associated with diving and compressed-air work. Dysbaric osteonecrosis is a term used to describe aseptic or avascular bone necrosis due to ischemia caused by gas bubbles, although the exact mechanism is. Dysbaric osteonecrosis (DON) was first identified in the s and was found to be relatively common in the s and early s in some.

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The results of univariate logistic regression analysis are detailed in Table 1. Diaphyseal damages are painless. Inadequate decompression is another big factor. Such prophylactic medication may be an ideal strategy for the prevention of DON.

This page was last edited on 12 Decemberat This leads to venous thrombosis causing retrograde arterial flow and increasing the overall intraosseous pressure. On the basis of this knowledge of steroid-induced osteonecrosis, we hypothesized that coagulation osreonecrosis or hyperlipidaemia might be present in divers with DON.

Add comment Close comment form modal. This process takes place over months to years and eventually causes disabling arthritisparticularly of the femoral head hip. The mean age of the study participants was Familial high plasminogen activator inhibitor with hypofibrinolysis, a new pathophysiologic cause of osteonecrosis?

Dysbaric osteonecrosis

There are many reasons for this discrepancy; principal among them is the small number of subjects. StatPearls Publishing; Jan.


The risk increased with greater deviations from safe decompression procedures. Enzymatic determination of total serum cholesterol. Such patients usually require joint replacement, which involves major and expensive surgery. After being first identified, osteonecrotic lesions are typically observed radiologically to monitor for any changes or potentially self-resolution.

We also observed that paradoxical, increasing pain during the first hyperbaric treatment might be a prognostic sign of DON development. Journal of Bone and Joint Surgery. When a lesion is juxta-articular, the articular surface may undergo collapse, resulting in osteoarthritic changes.

Dysbaric osteonecrosis in professional divers: Dysbaric osteonecrosis among professional divers: Lifestyle and dietary measures along with predive and postdive hydration may reduce the deleterious effects of venous stasis slow blood osteonwcrosis in the medullary cavities of bones following decompression. All analyses were performed using StatView software, version 5.

Diving, Dysbaric Osteonecrosis – StatPearls – NCBI Bookshelf

By using the most conservative decompression schedule reasonably practicable, and by minimizing the number of major decompression exposures, the risk of DON may be reduced. We recently showed with MRI that scuba divers who experienced repeated DCS which in 85 dysbraic of cases was shoulder pain developed definite DON lesions in 19 percent of cases. Introduction Dysbaric osteonecrosis is a type of avascular necrosis of the bone most commonly found in undersea divers and workers dyysbaric compressed air or gas.

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This suggests that preventative measures are being based upon an incomplete understanding of the pathophysiology osteonecrosiss the disease, and that other etiological factors are perhaps being overlooked. Serum levels osfeonecrosis apoA1 and apoB were measured by turbidimetric immunoassay [ 13 ].

Some anecdotal cases were observed in the past decade, but the few studies that attempted to determine the prevalence of DON osgeonecrosis recreational divers failed to demonstrate the presence of asymptomatic bone lesions using magnetic resonance imaging MRI. The following staging system is sometimes useful when managing lesions.

Microscopic cysts form, fill with necrotic material and there is massive necrosis with replacement by cancellous bone with collapse of the lesions. The recognition and management of hyperlipidaemia in adults: Divers should ensure adequate fluid intake to prevent hemoconcentration, which may predispose to DON. In these cases infection was the predominant etiology 1,2.

This result suggests that osteonrcrosis pharmacological approach incorporating the use of an anticoagulant may represent a potential strategy for the prevention of DON. Recognized risk factors for osteonecrosis include chronic steroid use, coagulopathies, alcoholism, smoking, antiretroviral drugs and many other conditions.